Background

Chronic urticaria is a highly frequent allergological and dermatological disorder. Many chronic urticaria patients are affected for years and exhibit a severe impairment of their quality of life. As of now, the epidemiology, duration, course, response to treatment and underlying causes of chronic urticaria are still ill defined. While a registry would be an appropriate tool to assess these features, this was, until recently, not available. Therefore, the Chronic Urticaria Registry (CURE) was set up as an academia-driven, open-ended registry for all subforms of chronic urticaria (chronic spontaneous urticaria and chronic inducible urticaria) to assess features which are, as of yet, not available. CURE is investigator-initiated and hosted by the non for profit organization Urticaria Network e.V. (UNEV) with support by GA²LEN, EADV and WAO. In addition, it is endorsed by the GA²LEN, EAACI and EADV Task Forces for chronic urticaria. The registry is open to all urticaria-treating physicians and centers.

 

Objectives

CURE aims to collect quality, real-life data on chronic urticaria patient characteristics, the course of disease, underlying causes, comorbidities, treatment responses, quality of life impairment and health care costs.

 

Core variables of CURE

• Demographic characteristics
• Duration and course of the disease
• Frequency of angioedema
• Underlying causes
• Comorbidites
• Triggering factors
• Treatment response
• Disease activity
• Disease control
• Quality of life impairment
• Direct health care costs
• Absence from work/school